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The MIBI scintigraphy (Methoxy-isobutyl-isomitril) is a special form of scintigraphy.
It is a highly sensitive technique for assessment of thyroid nodules and exclusion (or vast assurance) of a thyroid malignant tumor.
The MIBI scintigraphy is also used for diagnosing a parathyreoid adenoma.


With a negative result in MIBI scintigraphy, malignancy can be excluded almost 100% (the risk for malignancy is less than 1%).
But if a nodule shows positively in MIBI scintigraphy the chance of it being malignant rises to 15-20% depending on the data, which means, even if the MIBI scintigraphy shows a positive result, this doesn't mean the nodule is definitely classified as malignant. Constant check-ups are necessary.

The examination with MIBI scintigraphy is carried out in two steps:
About 10-15 minutes after the injection with a radioactive tracer, images of the thyroid will be made.
After about 4 hours another set of images will be made, amended with a SPECT.

A MIBI scintigraphy is essential - among other things - if you want to be treated with the latest technique - the Echotherapy that treats benign thyroid nodules. Check here for more information: Echotherapy. Before the treatment, malignancy has to be definitely excluded.


- Suspect - especially "cold" - nodules whose malignancy is unclear
- As preliminary assessment for qualification of Echotherapy treatment
- As reassurance for patients and decision support for therapy form
- Exclusion of malignancy